This tool can calculate various molecular parameters of PNAs, peptides as well as PNA-peptide-conjugates. For the calculation enter the full sequece (separated by spaces) including N- or C-Terminal modifications. Base monomers are all amino acids in single or three letter code (single letters: Caps, three letter code: First letter in upper case, subsequent letters in lower case).
Note: Building blocks with wrong capitalization like "gly" or "lYs" will not be recognized. To avoid reporting wrong numbers unkown building blocks are replaced by building block "UKN" which has such high values that this should not stay unnoticed.

• Modifications at the N-Terminus
  Modifications at the N-Terminus can simply be added as "first" building block, like "FAM K C D K G CONH2" or "TAMRA R C K N N CONH2"
• Modifications at the C-Terminus
  Modifications at the C-Terminus can simply be added as "last" building block, like "K C D K G COOH " or "R C K N N CONH2"
  Note: While it is not necessary to explicitly declare a free N-Terminus it is necessary to add "COOH" as group to denote a free C-terminus!
• Internal Modifications
  Internal modifications can be added to a building block in round brackets like "Lys(FAM) K C D K G COOH" or "Lys(TAMRA) R C K N N COOH"
• Special Modifications
  Besides typical fluorophores it is possible to use "p" to indicate a phosphorylation (e.g. "p Tyr") and a tilde at a Cystein residue to indicate a disulfide bond (e.g. "Ac C(~) K G N R C(~) COOH")